Category Archives: News

A research article in The Hindu on Prof. Kaushik’s research

Mimicking nature keeps implants bacteria-free

By mimicking tiny features of insect wings and shark skin, a team from Bengaluru’s Indian Institute of Science (IISc) has found a way to prevent bacterial infection on orthopaedic implants without using chemicals.

The team led by Kaushik Chatterjee from the Department of Materials Engineering at IISc relied purely on surface nanostructure to give the titanium metal used in implants the ability to kill bacteria.

Encouraging results were achieved in laboratory studies by making the shiny surface of implants rough through etching. The etched titanium surface is marked by randomly spaced nanopillars of 1 micrometre height and this makes it capable of killing infection-causing bacteria that adhere to the surface. The results were published in the journal Scientific Reports.

The rough surface of titanium was able to mechanically kill, within four hours of contact, nearly 95% of E. coli, 98% of Pseudomonas aeruginosa, and 92% of Mycobacterium smegmatis. Though only 22% of Staphylococcus aureus attached to the surface were killed within four hours, the efficiency shot up to 76% at the end of 24 hours.

Research on mechanism

Hospital-based bacterial infections from orthopaedic implants can lead to medical complications.

“We don’t know the precise mechanism by which the bacteria get killed. But we think the nanopillar architecture formed by dry etching mechanically ruptures the bacterial cells. Like in the case of the wing surface of cicadas, the bacterial cell membrane might be getting stretched by the nanopillars,” says Jafar Hasan from the Department of Materials Engineering at IISc and the first author of the paper.

Bacteria have high motion capability and adhere to the surface to form a biofilm. Since titanium surface is marked by sharp tips, the cell membrane gets mechanically damaged when in contact.

While the disease-causing bacteria get killed, stem cells of the kind that form bone were unaffected by the etched surface.

Unlike bacteria that have rigid membranes, the stem cells are bigger, softer and better able to conform and attach themselves to the rough surface.

“We want to etch actual implants and carry out trials on rats and rabbits to test for bactericidal activity and to understand how the rough implant behaves inside the body and study how the bone attaches itself to the implant and grows,” says Dr. Chatterjee, the corresponding author of the paper.

Alumni Day at IISc on 17 December 2016

The Institute is pleased to invite all its alumni back to our beautiful campus to join the Alumni Day Celebrations on Saturday, the 17th of December 2016. This is going to be the first of what is being planned as an annual event.

The individual Departments will put together a program for the morning of these day-long celebrations; the afternoon will feature an Institute-wide event in the Satish Dhawan Auditorium.

This is the first announcement to alert our alumni to mark their calendars, and to include these Celebrations in their Bangalore visit plans. We will come back with more information (and a detailed program) in due course.

We request you to inform your fellow alumni about this event.

And, we look forward to your participation in the Alumni Day Celebrations!

GIAN Course on Basics and Applications of Phase Field Modeling in Materials Science

Basics and Applications of Phase Field Modeling in Materials Science

A GIAN Course

5-9 December 2016
Department of Materials Engineering
Indian Institute of Science

We are pleased to announce a week long GIAN course on Basics and Applications of Phase Field Modeling in Materials Science to be held in the Indian Institute of Sciece campus during 5-9 December 2016. This is a 1-credit course taught by Prof. Mathis Plapp (Ecole Polytechnique, Paris, France), together with a team of instructors drawn from academic institutions and R&D labs in India.

The Course web page has more details.

GIAN Course: Process Metallurgy for 2016 and Beyond

Process Metallurgy for 2016 and Beyond

A GIAN Course

6-18 June 2016
Department of Materials Engineering
Indian Institute of Science

We are pleased to announce a 2-week long GIAN course on Process Metallurgy for 2016 and Beyond to be held in the Indian Institute of Sciece campus during 6-18 June 2016. This is a 2-credit course taught by Prof. Seshadri Seetharaman (Royal Institute of Technology, Stockholm, Sweden), together with a team of instructors drawn from academic institutions and R&D labs in India.

The Course web page has more details.

Congratulations to …

Students from our Department have won several awards in this year’s Annual Technical Meeting of the Indian Institute of Metals (held during 15-16 November 2015 at Coimbatore). Our hearty congratulations to:

  • M.S. Bhaskar for winning the P.K. Dasgupta Prize for the best paper presentation in the Ferrous Division.

  • Shalaka Shinde for winning the Second Prize for Oral Presentations in the Metal Sciences Division.

  • Devi Lal for winning the Second Prize for Poster Presentations in the Metal Sciences Division.

Congratulations to …

This year’s National Metallurgists Day Celebrations held on 14 November 2015 at Coimbatore saw a colleague and several alumni winning several awards. Our hearty congratulations to:

  • Prof. K. Chattopadhyay for winning the IIM Platinum Medal.

  • Prof. B.S. Murty (PhD-1992; now with IIT-M), for winning the IIM – G.D. Birla Gold Medal.

  • Dr. Dinesh Srivastava (PhD-1997; now with BARC) for winning the Metallurgist of the Year Award in Metal Sciences.

  • Prof. Nilesh Gurao (PhD-2011; now with IIT-K) for winning the Young Metallurgist of the Year Award in Metal Sciences.

Press coverage of Prof. K. Chattopadhyay Group’s research on mechanical behaviour of sea shells

We are pleased to note that several popular science media outlets have covered a recent paper from Prof. Chattopadhyay’s group in the journal Scientific Advances: Morphogenesis and mechanostabilization of complex natural and 3D printed shapes (by Chandra Sekhar Tiwary, Sharan Kishore, Suman Sarkar, Debiprosad Roy Mahapatra, Pulickel M. Ajayan, Kamanio Chattopadhyay).

Here’s a partial list: